Enalapril Maleate
Enalapril maleate is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing and widening blood vessels, which lowers blood pressure and reduces the workload on the heart, making it easier to pump blood throughout the body.
Dosage by Body Weight
For hypertension in adults, the standard starting oral dose is 5 mg once daily, adjusted based on patient response. For pediatric patients, dosing is based on body weight (typically starting at 0.08 mg/kg once daily up to a maximum of 5 mg). All dosages must be prescribed and monitored by a healthcare provider.
- Body Weight
- Below 5 kg
- Dose
- 0.08 mg/kg (approx 0.25 mg to 0.4 mg)
- Frequency
- Once daily
- Tracking Notes
- Safety and effectiveness in neonates and infants under this weight range have not been firmly established. Use only under strict specialist supervision.
- Body Weight
- 5-7 kg
- Dose
- 0.4 mg to 0.56 mg
- Frequency
- Once daily
- Tracking Notes
- Requires close monitoring of blood pressure, renal function, and serum potassium levels.
- Body Weight
- 8-10 kg
- Dose
- 0.64 mg to 0.8 mg
- Frequency
- Once daily
- Tracking Notes
- Dose may be adjusted upward by a physician if therapeutic response is inadequate.
- Body Weight
- 11-15 kg
- Dose
- 0.88 mg to 1.2 mg
- Frequency
- Once daily
- Tracking Notes
- Ensure the child is well-hydrated before starting therapy to prevent initial hypotension.
- Body Weight
- 16-20 kg
- Dose
- 1.28 mg to 1.6 mg
- Frequency
- Once daily
- Tracking Notes
- Do not exceed the maximum daily dose recommended by the pediatrician.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 0.08 mg/kg (approx 0.25 mg to 0.4 mg) | Once daily | Safety and effectiveness in neonates and infants under this weight range have not been firmly established. Use only under strict specialist supervision. |
| 5-7 kg | 0.4 mg to 0.56 mg | Once daily | Requires close monitoring of blood pressure, renal function, and serum potassium levels. |
| 8-10 kg | 0.64 mg to 0.8 mg | Once daily | Dose may be adjusted upward by a physician if therapeutic response is inadequate. |
| 11-15 kg | 0.88 mg to 1.2 mg | Once daily | Ensure the child is well-hydrated before starting therapy to prevent initial hypotension. |
| 16-20 kg | 1.28 mg to 1.6 mg | Once daily | Do not exceed the maximum daily dose recommended by the pediatrician. |
Formulation
Purpose
Used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack.
Generic Name
Enalapril MaleateBranded Drug Names
Enalapril Maleate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.